Altered Fractionation for Head and Neck Cancer
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چکیده
Delivery of therapeutic radiation in multiple sessions, or fractions, has been practiced since the discovery of radiation’s potential to cure malignancies. Initially, this was done out of practical necessity: Radiation was delivered at a low dose rate, and the treatment sessions had to be repeated to obtain the desired effect. Technologic improvements eventually allowed for treatments in one session, but clinical observations of improved outcomes with multiple fractions were noted in the 1920s, and the concept of fractionated radiation took hold.
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